InterSystems is a global leader in healthcare data management and interoperability, providing mission-critical technology that powers hospitals, health systems, and national infrastructures worldwide. Our products underpin trusted healthcare and financial systems where performance, availability, and security are non-negotiable.

As a Senior Program Manager, you lead large-scale, complex, cross-functional initiatives across product, engineering, cloud, and AI. You operate across organizational boundaries, translating objectives aligned to corporate strategy into coordinated, measurable outcomes. You support and operationalize the security strategy across the portfolio, ensuring effective execution through structured programs.

Security and performance are horizontal capabilities across our stack. You partner with product, engineering, and architecture to maintain consistent execution across the portfolio.

Key Characteristics

Thrives in high ambiguity, competing priorities
Owns outcomes at a program level
Connects strategy to execution (systems thinker)
Influences without authority
Execution-focused; manages complexity
Communicates clearly across technical and business audiences

Key Responsibilities

Program Strategy, Execution & Delivery
- Execute against existing program direction and strategic priorities, incorporating security and performance, and influencing future prioritization and execution
- Translate program strategy into execution plans across multiple teams and projects
- Lead concurrent projects to deliver program objectives
- Coordinate execution with program managers across cloud, database, interoperability, HealthShare, and AI-enabled systems
- Align scope, priorities, and dependencies to enable delivery
Cross-Functional Leadership & Stakeholder Management
- Orchestrate work across product, engineering, architecture, compliance, and operations
- Serve as integration point for dependencies, timelines, and deliverables
- Manage senior stakeholders, including executive engagement
- Communicate progress, risks, and decisions to support leadership action
- Run structured updates and program reviews to maintain alignment
Program Performance, Health & Continuous Improvement
- Monitor program performance and health against established KPIs, objectives, and milestones; contribute to KPI refinement
- Manage risks, issues, and dependencies; escalate when needed
- Maintain clear program visibility and enforce accountability
- Improve execution, coordination, and operational effectiveness

Qualifications

Bachelor’s degree in Computer Science, Business, Engineering, or related field; advanced degree preferred
10+ years leading large-scale, complex, cross-functional programs
Strong fundamentals in planning, scheduling, dependency and risk management
Experience managing performance to KPIs and driving accountability
Experience in cloud, healthcare, or enterprise technology environments preferred
Proven ability to influence senior stakeholders without direct authority
Strong communication and leadership skills
PMP or equivalent certification a plus

We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.

InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of factors including experience, education, skills, and performance.

Other compensation may include a discretionary annual variable target incentive.

The company also provides generous employee benefits including:

Medical, vision, and dental insurance
Short-term and long-term disability, and life insurance
401(k) Profit Sharing Contribution
Paid Time Off and Holidays
Parental Leave
Tuition reimbursement

The estimated base compensation range for this role is:

$147,000 - $185,000 USD

About InterSystems

InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.

InterSystems jobs

Senior Program Manager – Security and Performance

Never Miss a New Opportunity